Cone Health Ventures, the venture arm of Cone Health, actively pursues partnerships that deliver value for patients and the health system. Committed to innovation, they recognized an opportunity to improve care for individuals with chronic conditions like hypertension and diabetes, particularly those who were disengaged from the health system and potentially distrustful of traditional healthcare approaches.
Lirio Case Study

Background
Identification of Problem / Opportunity
Cone Health Ventures sought to address care gaps and advance health equity by connecting with these under-engaged patients. They needed a solution that could effectively engage these individuals and support their value-based care goals.
Solution Identification
Prinnovo engaged with Cone Health’s internal stakeholders to understand their specific challenges and requirements. We then conducted a thorough market analysis, identifying and vetting qualified solution providers. Our expertise allowed us to narrow down the options to a select group of partners who could address Cone Health’s unique needs.
Negotiation
Working closely with Cone Health’s leadership, Prinnovo facilitated the selection of Lirio, an innovative patient engagement platform, as the ideal partner. We ensured alignment of incentives within the Independent Practice Association (IPA) to guarantee that Cone Health, Lirio, and the patients themselves would all benefit from the partnership.
Co-Development and Pilot Process
Cone Health and Lirio collaborated to develop a targeted intervention program focused on engaging patients with hypertension and diabetes. This program aimed to encourage proactive health behaviors and reduce blood pressure within these populations.
Clinical/Operational Results
Since the program’s launch, Cone Health has seen significant impact:
- 40% of engaged patients scheduled primary care appointments
- 30% of patients in the diabetes intervention connected with a primary care provider
Vi-Anne, Cone Health’s Chief Nursing Officer, shared, “Lirio is helping Cone Health fulfill its brand promise to be ‘right here’ with the communities it serves, advancing health equity and reducing disparities across the population. By engaging patients directly on the platform with positive reinforcements, Lirio empowers them to take proactive steps toward better health, contributing to a more equitable healthcare experience.”
Scaling and Value Creation
The program not only improves individual outcomes but also helps patients stay healthier and avoid unnecessary hospital visits, aligning with Cone Health’s value-based care goals. This contributes to a more sustainable healthcare system focused on wellness rather than acute care. Prinnovo’s involvement enabled Cone Health Ventures to leverage a promising venture-backed solution that drives patient engagement and activation, particularly in areas of greatest need. Other health systems are now adopting this solution and realizing similar benefits.
Conclusion
Prinnovo’s partnership with Cone Health Ventures demonstrates our ability to help health systems identify, implement, and scale innovative solutions that address critical challenges and improve patient outcomes. By streamlining the process, fostering collaboration, and ensuring alignment, we unlock hidden value within healthcare organizations, driving meaningful change and advancing health equity.
This structure provides a clear and logical flow, highlighting the key aspects of the partnership and the value Prinnovo delivered at each stage.